Many artificially-derived cannabinoids do not occur naturally in hemp, or occur in such trace amounts that extracting and purifying them at scale is not practical. The following substances are typically artificially derived:
- Delta-8-THC
- Delta-10-THC
- “THCO" (delta-8-THC-O-acetate or delta-9-THC-O-acetate)
- HHC (hexahydrocannabinol)
- HHCO (hexahydrocannabinol-O-acetate)
- Delta-8-THCV
CBN is another substance that is often made as an artificially-derived cannabinoid. While it can occur naturally, manufacturers indicate that purified CBN being added to hemp products is more commonly created synthetically from CBD.
When in doubt, you can contact the manufacturer to find out whether their products are made with artificially derived cannabinoids.