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Safe Injections: One and Only Campaign

Oregon is a Partner State in the CDC's One & Only Campaign

Campaign logoThe One & Only Campaign is a public health campaign, led by the Centers for Disease Control and Prevention (CDC) and the Safe Injection Practices Coalition (SIPC), to raise awareness among patients and healthcare providers about safe injection practices. The campaign aims to eradicate outbreaks resulting from unsafe injection practices.

Raising awareness among healthcare providers and patients is critical to eliminating preventable infections caused by unsafe injections.

Injection and Needle Safety Toolkit

Although injections and needle use in professional settings are generally safe, unsafe practices do happen and may cause serious harm.

Unsafe practices, like reusing vials or syringes, have the potential to spread disease by cross-contaminating body fluids. Since 2001, more than 150,000 people in the U.S. have been notified of potential exposure to viral hepatitis and HIV due to lapses in injection and needle safety.

Do your part. Three ways to help stop these infections:

  1. Join the Oregon One and Only Campaign mailing list. Email for more information.
  2. Learn about best practices by using this toolkit.
  3. Share what you learn from the toolkit with those in your workplace.
  4. Read our latest injection safety newsletter.

Disclaimer: The resources below contain overlapping information on best practices, but are by no means comprehensive, as new resources continually emerge. In addition, the links provided do not serve as an endorsement of the organizations.

Toolkit Contents

For the Public

For Health Professionals


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For the Public

What to know about receiving healthcare involving needles.


Needle Safety

Syringe Exchange Program

Resources for Self-Injections

Needle Disposal

For Health Professionals

Guidelines and Recommendations

  • CDC's One & Only CampaignCampaign logo
    : A collection of injection and needle safety resources that includes free print materials, multimedia materials and additional resources.
  • WHO Injection Safety Campaign
    : A collection of best practice resources that provides guidelines, educational and evaluation tools and print materials.
  • Safe Injection Practices
    Online Training Module: Interactive 20 minute online training that describes the impact of unsafe needle and injection practices, CDC recommendations for best practices and how health professionals can champion needle and injection safety in their facilities. Developed by the OHA HAI program. Note: After clicking the link above, you will be prompted to create an iLearn account and will gain access to additional training resources. Please use Internet Explorer or Microsoft Edge for best results. 
  • Safe Injection Practices Overview (pdf)
    PowerPoint: HAI Program presentation that describes the impact of unsafe needle and injection practices, CDC recommendations for best practices, and how health professionals can champion needle and injection safety in their facilities.
  • CDC and CMS: Nursing Home Infections Preventionist Training, Module 8 - Injection Safety (relevant to a broad audience)
    Online Training Module: Provides an overview of injection safety, along with a review of recommended practices and consequences of failure to follow safe injection practices. This module is organized into five lesson and will take approximately 55 minutes to complete. 
  • CDC Grand Rounds: Preventing Unsafe Injection Practices in the U.S. Health-Care System
    MMWR: CDC overview of the impact of unsafe injection practices, state and federal government response, public health's role, and an illustrative case study.
  • CDC Guideline for Isolation Precautions: Preventing Transmission of Infectious Agents in Healthcare Settings (2007)
    Guidelines: The CDC summary of recommendations for infection control in healthcare settings, guidelines that, as of 1/1/18, are required for licensed health professionals in Oregon (see above).

Rules and Regulatory Guidance

Tools for Facility Assessment


Aseptic Technique

Skin Preparation

Rubber Septum

Accessing Central Lines


Needle Safety

What to Do After a Needle-stick

Waste Disposal


Medication and Treatment Management



Mixing (Admixture)

Vial Safety

Special Topics


Diabetes Care


Disease Transmission and Outbreaks


Specialty-Specific Resources


Blood Draw/Phlebotomy



Dry Needling


Point of Care Testing Involving Finger-stick


  • CDC: Infection Prevention in Outpatient Surgery Centers
    PowerPoint Presentation: A 2012 presentation given by Dr. Melissa Schaefer (CDC) on the impact of best practice breaches, as well as a summary of guidelines for injection safety and ensuring aseptic technique is followed.

Micro Needling/Dermal Needling

Orthopedic and Pain Management



Wet Cupping

More Resources for Health Professionals

  • Oregon Health Alert Network
    Web System: Oregon Health Authority provides a regional network that allows for sharing of health data among health professionals, public safety professionals, and public health partners.

  For more information, contact Roza Tammer at or call 971-673-1074.


Dolan SA, Arias KM, Felizardo G, Barnes S, Kraska S, Patrick M, Bumsted A. APIC position paper: Safe injection, infusion, and medication vial practices in health care. American Journal of Infection Control 2016; 44(7):750-757.