Public Health Division

Lab Test Details

Hantavirus Antibodies, IgG and IgM
Updated	12/8/2025
Other Names	HPS Pulmonary Syndrome; Sin Nombre Virus
How to Order	On the OSPHL Virology/Immunology Test Request Form, in the "Referral Testing/Send-Outs" section, write in the test(s) ordered under "Non-CDC Referral."
Availability	All clients, for confirmation of positive results from clinical laboratories Approval by an Acute and Communicable Disease Prevention Section (ACDP) epidemiologist required.
Performed	Upon request
Time to Reporting	Time to reporting set by reference lab, the Idaho Bureau of Laboratories (IBL)
CPT Code

Specimen Collection Details
Collection, Specimen Volume, Handling, Transportation	One 7 mL red top or serum separator tube (SST). Plasma or post-mortem heart blood is also acceptable. Complete instructions are provided in the Idaho Bureau of Laboratories Clinical Specimen Submission Guide. Scroll to or search for the Hantavirus Serology instructions. Transport specimens to the Oregon State Public Health Laboratory (OSPHL). OSPHL will forward specimens to IBL for testing. IBL will not accept specimens directly from Oregon healthcare providers and laboratories.
Rejection Criteria	Per the IBL Clinical Specimen Submission Guide: specimens containing observable particulate material, suspended fibrin particles or aggregates; severely hemolyzed or heat-inactivated specimens. Additional criteria may be provided in the IBL Specimen Submission Guide. Specimens are also subject to the requirements of the OSPHL Specimen Submission Policy (pdf). effective 3/11/2025
Comments	The Idaho Bureau of Laboratories Hantavirus IgM &IgG assay is specific for Sin Nombre Virus only. If a different Hantavirus is suspected, contact OSPHL or ACDP for guidance prior to submitting specimens. For additional information or assistance, please contact OSPHL at 503-693-4100.

Method Details
Methodology	Methods are provided by the testing laboratory.
Performance Specifications	Method performance specifications are available by contacting IBL.

Change Log
12/8/2025	Changes throughout due to change of reference lab; review as new
1/30/2025	Reviewed, no changes
12/9/2024	Changes throughout; review as new